Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp86 | Diabetes (1) | ECE2016

Novel biomarkers of chronic kidney disease in diabetes

Zuraeva Zamira , Mikhaleva Olga , Vikulova Olga , Ilyin Aleksandr , Shamkhalova Minara , Shestakova Marina , Dedov I.I.

Background and aims: Microalbuminuria (MA) is not specific predictor of early stages of chronic kidney disease (CKD) in diabetes. We investigate several markers that might be useful in assessing early kidney damage in T1DM and T2DM patients additional to MA.Materials and methods: We examined 111 patients (T1DM/T2DM: 51/60) with AER<20 mg/l (n=80); <199 mg/l (n=18); ≥200 mg/l (n=13). Biomarkers of kidney damage (c...

ea0041ep484 | Diabetes complications | ECE2016

Association of the PPARG2 Pro12Ala, TNFα G(308)A and G(238)A, Lipc C(-514)T, Ace I/D, Slco1b1 Val174ala polymorphism with endothelial function and atorvastatin response in type 2 diabetic patients

Lebedeva Nadezhda , Vikulova Olga , Nikitin Alexei , Shamkhalova Minara , Shestakova Marina , II Dedov

Aim: To assess the association of the endothelial dysfunction (ED) parameters and the lipid-lowering response to atorvastatin therapy in patients with T2D with genetic markers of inflammation.Methods: We include 97 T2D patients with first prescribed atorvastatin 10–20 mg: M/F 26/71; mean age 57 years. After 12 month of statin therapy, patients had fasting lipid profiles and ED parameters repeated. For ED evaluation, we performed pulse wave analysis ...